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Allele : Dnajc2<em1(IMPC)J> DnaJ heat shock protein family (Hsp40) member C2; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6316603 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Dnajc2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GATGGGCAATGATTCTTACA and TCCAAAGCGAGGCTTCAGGC, which resulted in a 342 bp deletion beginning at Chromosome 5 position 21,781,162 bp and ending after 21,781,503 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001284504 (exon 3) and 266 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 85 and early truncation 5 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

4 Publication categories

Trail: Allele