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Allele : Rcor3<em1(IMPC)J> REST corepressor 3; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6317336 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Rcor3
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGATGGAACCAGGCCTCACG and TTAGTAAAGGTACCACGACA, which resulted in a 474 bp deletion beginning at Chromosome 1 position 192,124,003 bp and ending after 192,124,476 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000504238 (exon 6) and 349 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause early truncation after amino acid 170. There is a 1 bp insertion C at the deletion site.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele