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Allele : Ano6<em6(IMPC)Tcp> anoctamin 6; endonuclease-mediated mutation 6, The Centre for Phenogenomics

Primary Identifier  MGI:6323005 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ano6
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele from project TCP0236 was generated at The Centre for Phenogenomics by injecting Cas9 ribonucleoprotein complex with a single guide RNA having sequence GGATCGGGTCTGTCCCGTTG. The repaired allele had a frame shift deletion of 2 nucleotides, c.C1482- and c.G1483-. This shifts the reading frame at p.N494K and introduces a stop codon at p.Y547*.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories

Trail: Allele