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Allele : Tg(Drd2-flpo)3BBsab transgene insertion 3B, Bernardo Sabatini
Primary Identifier  MGI:6378545 Allele Type  Transgenic
Attribute String  Recombinase Gene  Tg(Drd2-flpo)3BBsab
Strain of Origin  FVB Is Recombinase  true
Is Wild Type  false
molecularNote  A transgene derived from a BAC clone bMQ313M14 containing the mouse Drd2 (dopamine receptor D2) promoter modified to no longer drive expression of dopamine 2 receptors and expresses codon-optimized Flp (flpo) recombinase. No other genes are reported to be expressed from the BAC. The transgenic vector was introduced to FVB embryos. A loxP-flanked neomycin selection cassette originally located just 3' of Flp has been excised. This is founder line 3B.
  • mutations:
  • Insertion
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