| Primary Identifier | MGI:6343228 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Armc3 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TGTCACATCAAAATTAACAG and GAGAATACCCTGAGTGAAAG, which resulted in a 406 bp deletion beginning at Chromosome 2 position 19,235,420 bp and ending after 19,235,825 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000290542 (exon 3) and 288 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 16 and early truncation 16 amino acids later. There is a 6 bp deletion (CCTTTC) 15 bp downstream the 406 bp deletion. |
