| Primary Identifier | MGI:6343242 | Allele Type | Targeted |
| Attribute String | Conditional ready, Null/knockout, Reporter | Gene | Thyn1 |
| Transmission | Germline | Strain of Origin | C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | This KO first allele (reporter-tagged insertion with conditional potential) was generated using EUCOMM vector PRPG00147_X_4_A07. The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exons. The critical exons 3-7 are thus flanked by loxP sites. For vector details, see Thyn1tm1a(EUCOMM)Hmgu. |
