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Allele : Zbtb37<em1(IMPC)J> zinc finger and BTB domain containing 37; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6324240 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Zbtb37
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TCTAGGATCAGTAATTGCCA and AGTTCAAACATCCCTACAAA, which resulted in a 1328 bp deletion beginning at Chromosome 1 position 161,031,517 bp and ending after 161,032,844 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000947438 (exon 3) and 368 bp of flanking intronic sequence including the splice acceptor and donor and start site and is predicted to generate a null allele.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele