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Allele : Rest<tm1.2Bban> RE1-silencing transcription factor; targeted mutation 1.2, Botond Banfi

Primary Identifier  MGI:6378686 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Rest
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site and a frt-flanked neomycin resistance gene were inserted upstream of exon 4 and a second loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the selection cassette and cre-mediated recombination deleted exon 4. Deletion of exon 4 prevents the production of the exon4-containing splice form without reducing expression of the form lacking this exon.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Rest<deltaEx4>,
  • Rest<deltaEx4>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele