| Primary Identifier | MGI:6355954 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Nr5a1 |
| Strain of Origin | B6D2F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 mutagenesis was used with a gRNA and a donor oligonucleotide to create a C to T mutation (c.274C>T) that changes arginine codon 92 into an tryptophan codon (p.R92W). This mutation mimics a mutation found in patients with 46,XX testicular/ovotesticular disorders of sex development (DSD). |
