Primary Identifier | MGI:6356000 | Allele Type | Targeted |
Attribute String | Inserted expressed sequence, Reporter | Gene | Ret |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A gene cassette composed of floxed human RET gene cDNA, an SV40 intron polyA followed by mCherry reporter gene and a neomycin resistance marker (Neo) that was flanked by FRT sites was inserted into the first coding exon of the mouse Ret gene. The neomycin resistance cassette was removed via FLP-mediated recombination in the germline. |