| Primary Identifier | MGI:6356394 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Plekhg2 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TAACGGCTAGAAGTAGGGCA and TCCCATGACAAGACTCCAGA, which resulted in a 1561 bp deletion beginning at Chromosome 7 position 28,367,390 bp and ending after 28,368,950 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001262284 to ENSMUSE00001304994(exons 5-9) and 957 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 156 and early truncation 5 amino acids later. |
