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Allele : Ripk3<tm3.1Vmd> receptor-interacting serine-threonine kinase 3; targeted mutation 3.1, Vishva M Dixit
Primary Identifier  MGI:6356682 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Ripk3
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence 5'-GTGCAGATTGGG-3', encoding RIP homotypic interaction motif (RHIM) residues VQIG, was replaced with the sequence 5'-GCAGCCGCGGCT-3', coding for AAAA. An FRT site flanked neomycin selection cassette inserted into intron 9 at position chr14:55,785,501 (GRCm38, reverse strand) was deleted from the targeted embryonic stem cells before microinjection.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Ripk3<RHIM>,
  • Ripk3<RHIM>,
  • Ripk3<RHIM>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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