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Allele : Trp53<tm3.1Wgu> transformation related protein 53; targeted mutation 3.1, Wei Gu
Primary Identifier  MGI:6357928 Allele Type  Targeted
Gene  Trp53 Transmission  Germline
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
molecularNote  All seven lysine codons in exon 11 were mutated to glutamine (p.K367Q, p.K369Q, p.K370Q, p.K378Q, p.K379Q, p.K383Q, p.K384Q) and a loxP site flanked neomycin resistance gene cassette was inserted into intron 10. Cre-mediated recombination removed the neo cassette. The mutant protein mimics the acetylated form of the protein.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Trp53<KQ>,
  • Trp53<KQ>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

6 Publication categories

Trail: Allele




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