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Allele : Prkdc<tm1.1Shzh> protein kinase, DNA activated, catalytic polypeptide; targeted mutation 1.1, Shan Zha
Primary Identifier  MGI:6357215 Allele Type  Targeted
Gene  Prkdc Transmission  Germline
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
molecularNote  The conserved aspartic acid at position 3922 was mutated to an alanine (p.D3922A) and a floxed neo cassette was inserted ~600 bp upstream via homologous recombination. Cre mediated recombination removed the neo cassette. This mutation expresses a catalytically inactive mutant protein.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • DNA-PKcs<KD>,
  • DNA-PKcs<KD>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

3 Publication categories

Trail: Allele




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