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Allele : Prkdc<tm2.1Shzh> protein kinase, DNA activated, catalytic polypeptide; targeted mutation 2.1, Shan Zha
Primary Identifier  MGI:6357216 Allele Type  Targeted
Attribute String  Not Specified Gene  Prkdc
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  The conserved serine at position 2053 was mutated to an aspartic acid and an FRT flanked neo cassette was inserted in the upstream intron via homologous recombination. Flp mediated recombination removed the neo cassette. This mutation produces a protein with a phosphomimetic substitution.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • DNA-PKcs<SD>,
  • DNA-PKcs<SD>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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