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Allele : Foxb2<em1(IMPC)J> forkhead box B2; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6357983 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Foxb2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CGGTGTTGGTGCATTCTTAG and TAGGAACTCTTCCCTGGCCG, which resulted in a 1274 bp deletion beginning at Chromosome 19 position 16,872,358 bp and ending after 16,873,631 bp (GRCm38/mm10). This mutation deletes 1274 bp of ENSMUSE00000462680 (exon 1) and is predicted to cause a change of amino acid sequence after residue 3 and truncation 33 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele