| Primary Identifier | MGI:6363569 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Topors |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CCGTAACTAACTGTTCACCC and GGTACTTCCCCAAAGGTAAA, which resulted in a 3749 bp deletion beginning at Chromosome 4 position 40,259,541 bp and ending after 40,263,289 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000345531 (exon 3) and 268 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 67 and early truncation 12 amino acids later. |
