Primary Identifier | MGI:6360640 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Amelx-icre)876Ppap |
Strain of Origin | C57BL/6 | Is Recombinase | true |
Is Wild Type | false |
molecularNote | The transgene was created by modifying BAC by replacing exon 2 of mouse Amelx gene with an improved cre recombinase gene (icre). An FRT-flanked kanomycin resistance cassette was removed prior to injection. 4 independent BAC founder lines (854, 863, 872, and 876) were collected. Line 876 showed the strongest X-gal staining in ameloblasts. However, non-specific staining in the osteoclasts and osteoblasts are noted. |