| Primary Identifier | MGI:6359751 | Allele Type | Targeted |
| Attribute String | Recombinase | Gene | Pdx1 |
| Transmission | Germline | Strain of Origin | (129S6/SvEvTac x C57BL/6NCrl)F1 |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | The targeting construct was generated such that exon 2 of the mouse Pdx1 gene in a BAC clone RP23-59N19 was replaced with a modified exon 2 in which a 2A peptide sequence followed by the Dre sequence was inserted immediately before the stop codon of the Pdx1-coding sequence. The FRT-flanked neomycin selection cassette (neo) was placed at the beginning of the 3' untranslated sequence which was removed by crossing chimeric mice with Flpo mice. |
