| Primary Identifier | MGI:6358741 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Hnrnph1 |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Left TAL effector (50,191,867-50,191,883 bp) and right TAL effector (50,191,899-50,191,915 bp) separated by the FokI cleavage zone was used to introduce a 16 bp frameshift deletion in the first coding exon (exon 4). The mutation results in a premature stop codon. Founder 28 was established. qPCR analysis demonstrated a significant downregulation of transcript levels in heterozygous mutant mice. |
