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Allele : Ifngas1<em1Oshea> Ifng antisense RNA 1; endonuclease-mediated mutation 1, John O'Shea

Primary Identifier  MGI:6359822 Allele Type  Endonuclease-mediated
Gene  Ifngas1 Strain of Origin  (C57BL/6J x DBA/2J)F1
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/Cas9 genome editing is used to insert a bovine growth hormone cassette and a poly adenylation sequence 70 base pairs after the transcription start site. The mutation results in premature termination of Ifngas1 transcription without disrupting the local chromatin architecture.
  • mutations:
  • Insertion
  • synonyms:
  • Ifng-as1 PolyA KI,
  • Ifng-as1 PolyA KI
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele