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Allele : Sftpc<tm1Mfbs> surfactant associated protein C; targeted mutation 1, Michael F Beers
Primary Identifier  MGI:6360467 Allele Type  Targeted
Attribute String  Epitope tag Gene  Sftpc
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence coding for an N-terminal hemagglutinin (HA) tag was inserted into exon 1 immediately after the ATG start codon, isoleucine codon 73 (ATC) in exon 3 was changed to threonine (p.I73T), and an FRT site flanked neomycin resistance gene and gb2-promoter-driven kanamycin resistance gene cassette into intron 1. The neo/kana cassette interferes with the expression of the gene and mRNA expression is at 15%.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Sftpc<I73T-neo>,
  • Sftpc<I73T-neo>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele




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