| Primary Identifier | MGI:6390565 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Scn2a |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 editing was used to introduce a single nucleotide change AAA to GAA, resulting in substitution of glutamate for lysine at position 1422 (K1422E). This corresponds to the neurodevelopmental disorder-associated p.K1422E pathogenic variant in humans. |
