| Primary Identifier | MGI:6382419 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Dnajc6 |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/cas9 endonuclease-mediated genome editing is used to create an amino acid substitution at position 857 altering arginine to glycine (R857G; AGG to GGC) in the Hspa8 binding domain of the gene. The mutation is orthologous to the pathogenic human R927G allele associated with juvenile Parkinsonism. |
