Primary Identifier | MGI:6364869 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Caskin1 |
Transmission | Germline | Strain of Origin | C57BL/6N |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site and PGK-neo cassette were inserted into intron 1 and a second loxP site was inserted in intron 6. Cre-mediated recombination deleted exons 2-6 and the PGK-neo cassette. Western blot analysis confirmed absence of protein in the spinal dorsal horn and hippocampus. |