Primary Identifier | MGI:6364882 | Allele Type | Endonuclease-mediated |
Attribute String | Humanized sequence, Hypomorph | Gene | Tfap2b |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A 4-base deletion (c.435_438delCCGG or c.439_442delCCGG) was created in exon 2 with two sgRNAs and a donor oligonucleotide using CRISPR/Cas9 technology. This deletion mimics one found in a family with patent ductus arteriosus (PDA). |