Primary Identifier | MGI:6367822 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Ttk |
Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
Is Recombinase | false | Is Wild Type | false |
Project Collection | IMPC |
molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ACACCCACAAGAAACCCTGT and GATCCCTCAGAGTTACAGTT, which resulted in a 511 bp deletion beginning at Chromosome 9 position 83,839,051 bp and ending after 83,839,561 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000474185 (exon 3) and 297 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 46 and early truncation 48 amino acids later. |