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Allele : Ttk<em1(IMPC)J> Ttk protein kinase; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6367822 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ttk
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ACACCCACAAGAAACCCTGT and GATCCCTCAGAGTTACAGTT, which resulted in a 511 bp deletion beginning at Chromosome 9 position 83,839,051 bp and ending after 83,839,561 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000474185 (exon 3) and 297 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 46 and early truncation 48 amino acids later.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Ttk<->,
  • Ttk<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele