| Primary Identifier | MGI:6367824 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(RBP3-Prph2*)#Naash |
| Strain of Origin | CD-1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgene insert contains the following elements: the human interstitial retinol binding protein 3 promoter, the mouse Prph cDNA with two mutations (p.R172W and p.P341Q), and SV40 poly(A) signal sequence. The Arg172Trp mutation mimics the mutation found in some human patients presenting with retinal degeneration. The Pro341Gln mutation was made so the peptide can be identified by monoclonal antibody 3B6. |
