| Primary Identifier | MGI:6362057 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Dpf3 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AGAGCCTCGCCACAGCAGGA and GTTTTCCTGCTGGGAAAGCA, which resulted in a 342 bp deletion beginning at Chromosome 12 position 83,315,268 bp and ending after 83,315,609 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000275415 (exon 6) and 263 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 175 and early truncation 69 amino acids later. |
