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Allele : Nrg1<em2(cre/ERT2)Bzsh> neuregulin 1; endonuclease-mediated mutation 2, Bin Zhou
Primary Identifier  MGI:6361465 Allele Type  Endonuclease-mediated
Attribute String  Conditional ready, Inducible, Recombinase Gene  Nrg1
Strain of Origin  Not Specified Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  The mouse line was generated by homologous recombination using the CRISPR/Cas9 technology. A complementary DNA encoding Cre recombinase fused with 2 rox sequences flanking a mutant form of the ESR hormone-binding domain (ERT2) was inserted into the translational start codon ATG of the Nrg1 gene and followed by a polyadenylation sequences.
  • mutations:
  • Insertion
  • synonyms:
  • Nrg1-CrexER,
  • Nrg1-CrexER
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Trail: Allele

Genome

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0 Mutation Involves

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Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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