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Allele : Tg(Trpm8-HBEGF/EGFP)M8Dmck transgene insertion M8, David McKemy
Primary Identifier  MGI:6379569 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Trpm8-HBEGF/EGFP)M8Dmck
Strain of Origin  (C57BL/6 x DBA/2)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  A 130-200 kbp bacterial artificial chromosome (BAC) RPC1-22 clone 553 H3 containing the entire ~80 kbp mouse Trpm8 gene was modified to insert a simian diphtheria toxin receptor / enhanced green fluorescent protein fusion gene sequence (DTR/EGFP) followed by an SV40 polyA sequence into exon 2 of Trpm8 locus on the BAC (disrupting the Trpm8 coding region). No other loci on the BAC were altered. The BAC may also include the Ugt1a2, Dnajb3, Ugt1a1, Mroh2a, Hjurp and Spp2 loci.
  • mutations:
  • Insertion
  • synonyms:
  • Trpm8<DTR>,
  • Tg(Trpm8-DTR/EGFP)M8Dmck,
  • Tg(Trpm8-DTR/EGFP)M8Dmck,
  • Trpm8<DTR>
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1 Feature

Trail: Allele

Genome

2 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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2 Publication categories

Trail: Allele




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