| Primary Identifier | MGI:6379576 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Sting1 |
| Transmission | Germline | Strain of Origin | C57BL/6N-A<tm1Brd> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The targeting vector was designed to insert an FRT-flanked neomycin resistance (neo) cassette downstream of exon 5 of the gene. Three common alternative allelic variants (R71H-I229A-R292Q) equivalent to those found in humans (R71H-G230A-R293Q) were introduced as follows - exon 3 was modified to harbor R71H, exon 6 modified to harbor G230A, and exon 7a was modified to harbor R293Q. Flp-mediated recombination removed the FRT-flanked neo cassette. |
