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Allele : Insyn2b<em1(IMPC)J> inhibitory synaptic factor family member 2B; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6385688 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Insyn2b
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CCCAGCAAAGTATGAAAGTG and AAGCTCACGCTCTCACTGAA, which resulted in a 1327 bp deletion beginning at Chromosome 11 position 34,401,977 bp and ending after 34,403,303 bp (GRCm38/mm10). This mutation deletes 1327 bp of ENSMUSE00000881654 (exon 2) and is predicted to cause a change of amino acid sequence after residue 6 and early truncation 26 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele