| Primary Identifier | MGI:6385876 | Allele Type | Targeted |
| Gene | Trf | Transmission | Germline |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Two A to T nucleotide substitutions were introduced resulting in a tyrosine to phenylalanine change at amino acid 114 (Y114F) and at amino acid 207 (Y207F). A FRT-flanked neomycin resistance cassette was inserted downstream of the two mutations. These two mutations abrogate iron binding in the N lobe of transferrin. |
