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Allele : Bdnf<tm1.1Xen> brain derived neurotrophic factor; targeted mutation 1.1, Taconic Biosciences
Primary Identifier  MGI:6392346 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Bdnf
Transmission  Germline Strain of Origin  C57BL/6NJcl
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 9 was replaced with a floxed neomycin resistance cassette and a modified exon 9 with the nucleotide substitution of GCT to ATG that results in the amino acid substitution of methionine for valine at position 68. This mutation mimics a human polymorphism associated with psychiatric disorders. Cre-mediated recombination removed the selection cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • BDNF<met>,
  • BDNF<met>,
  • Met68BDNF KI,
  • Met68BDNF KI
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

5 Publication categories

Trail: Allele




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