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Allele : Myd88<tm1.1Mpa> myeloid differentiation primary response gene 88; targeted mutation 1.1, Manolis Pasparakis

Primary Identifier  MGI:6392915 Allele Type  Targeted
Attribute String  Conditional ready Gene  Myd88
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 2-6 of the gene were flanked by loxP sites and a cassette consisting of an adenoviral splice acceptor site fused to an IRES and a GFP gene ws inserted downstream of the second loxP site. An frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. Upon cre-mediated recombination, exons 2-6 are removed and the GFP reporter gene is expressed under the endogenous promoter.
  • mutations:
  • Insertion
  • synonyms:
  • MyD88-floxed,
  • MyD88-floxed
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

13 Publication categories

Trail: Allele