| Primary Identifier | MGI:6393601 | Allele Type | Targeted |
| Attribute String | Inducible, Recombinase | Gene | Ndnf |
| Transmission | Germline | Strain of Origin | C57BL/6J |
| Induced With | tamoxifen | Is Recombinase | true |
| Is Wild Type | false |
| molecularNote | The targeting vector was designed to insert an internal ribosome entry site (IRES) fused to a Cre/ERT2 fusion gene (Cre recombinase fused to a human estrogen receptor ligand binding domain) into the 3' UTR in exon 4 of the neuron-derived neurotrophic factor (Ndnf) gene. The construct also included a frt-flanked neomycin resistance cassette. After homologouse recombination in ES cells, the resulting chimeric mice were bred with flp recombinase expressing mice to remove the neo cassette. |
