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Allele : Col1a1<tm1(RHOA*Y42C)Abass> collagen, type I, alpha 1; targeted mutation 1, Adam Bass

Primary Identifier  MGI:6393676 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence Gene  Col1a1
Transmission  Germline Strain of Origin  C57BL/6 and 129
Is Recombinase  false Is Wild Type  false
description  The allele was made in MESC10 ES cells that carry an FRT-PGK-neomycin-FRT (Flp in) site downstream of the mouse Col1a1 gene.
molecularNote  A loxP-Stop-loxP-Human RHOA cDNA cassette, modified with a Y42C amino acid mutation (nucleotides TAT to TGT) in RHOA, was introduced to an intergenic region downstream of the mouse Col1a1 gene via Flp recombinase-mediated homologous recombination.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • LSL-RHOA<Y42C>,
  • LSL-RHOA<Y42C>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele