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Allele : Pik3cb<tm2Bvan> phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; targeted mutation 2, Bart Vanhaesebroeck
Primary Identifier  MGI:7563992 Allele Type  Targeted
Attribute String  Reporter Gene  Pik3cb
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct inserted after the STOP codon in the last exon (24) a loxP site, IRES sequence, lacZ reporter gene, neomycin resistance cassette and loxP site. Exon 22 was modified by nucleotide substitutions to accomplish the amino acid substitution of alanine for aspartic acid at position 931 (D931A).
  • mutations:
  • Insertion,
  • Single point mutation
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

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Trail: Allele




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