| Primary Identifier | MGI:7564547 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Gata2 |
| Transmission | Germline | Strain of Origin | C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Leucine codon 359 (TTA) in exon 5 was changed to valine (GTA) (p.L359V) and a loxP site flanked neomycin resistance gene was inserted into an intron. The mutation is the equivalent of the same human mutation associated with acute myeloid leukemia (AML) and myelomonocytic transformation of chronic myelogenous leukemia (CML). |
