| Primary Identifier | MGI:7564128 | Allele Type | Endonuclease-mediated |
| Attribute String | Modified isoform(s) | Gene | Syngap1 |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Intron 10 was targeted with two sgRNAs using CRISPR/Cas9 technology, resulting in a 268 bp deletion (GRCm39:chr17:27178158-27178425). This deletion eliminates the alternative 3' splice acceptor site that is used for NMD-mediated transcriptional regulation. |
