| Primary Identifier | MGI:6393876 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Tmprss9 |
| Transmission | Germline | Strain of Origin | C57BL/6NTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A gene trap cassette containing an FRT site, attB site, Puromycin resistance gene, attP site, human growth hormone poly(A) signal sequence, and FRT site was inserted between exon 1 and exon 2. In addition, exon 2 was flanked by loxP sites. The Puromycin resistance gene was removed via PhiC31-mediated recombination. The human growth hormone poly(A) signal sequence was removed via Flp-mediated recombination. Cre-mediated recombination deleted exon 2. Deletion of exon 2 leads to a frameshift and premature stop codon in exon 3. |
