| Primary Identifier | MGI:6404631 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Tardbp |
| Transmission | Germline | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The nucleotide G at position 943 was substituted for A resulting in an A to T change at amino acid 315 in exon 6. A loxp-flanked neomycin-resistant gene that inserted in intron 4 was removed via cre-mediated recombination. The A315T mutation is seen in several European families with amyloid lateral sclerosis. |
