| First Author | Maysinger D | Year | 2007 |
| Journal | Nano Lett | Volume | 7 |
| Issue | 8 | Pages | 2513-20 |
| PubMed ID | 17638392 | Mgi Jnum | J:288543 |
| Mgi Id | MGI:6433144 | Doi | 10.1021/nl071611t |
| Citation | Maysinger D, et al. (2007) Real-time imaging of astrocyte response to quantum dots: in vivo screening model system for biocompatibility of nanoparticles. Nano Lett 7(8):2513-20 |
| abstractText | Astrocytes are the principle macroglial brain cells. They are activated by different stressors and brain injuries. Quantum dots (QDs) can cause oxidative stress. This study shows a real-time imaging of primary cortical cultures and assessment of QD-induced activation of astrocytes in the brains of transgenic mice with the luciferase gene driven by the murine astrocyte promoter. This approach may be widely applicable for assessing the astroglia/tissue response to nanoparticles in live animals. |
