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Allele : Fmr1<tm1Sud> fragile X messenger ribonucleoprotein 1; targeted mutation 1, Thomas C Sudhof

Primary Identifier  MGI:6441026 Allele Type  Targeted
Attribute String  Conditional ready Gene  Fmr1
Transmission  Germline Strain of Origin  (C57BL/6 x 129S6/SvEvTac)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A cassette incorporating FRT1-loxP1-FRT2-neomycin-FRT1-loxP2 and a copy of Exon3 carrying a 3xStop and mVenus-loxP2-FRT2 was introduced to intron 2, and a loxP1 site was placed in intron 3. The neomycin-FRT1-loxP2-Exon3*(Stop)-IRES-mVenus-loxP2 is skipped and non-functional, without Stop or fluorescent properties.
  • mutations:
  • Insertion
  • synonyms:
  • Fmr1 cKO,
  • Fmr1 cKO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele