| Primary Identifier | MGI:6416109 | Allele Type | Targeted |
| Attribute String | Conditional ready, Humanized sequence | Gene | Eif2b5 |
| Transmission | Germline | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Residue arginine 132 was changed to histamine, loxP sites were inserted flanking some of the exons including the mutation, and a FRT-flanked neomycin resistance cassette was inserted upstream of the mutation. The neomycin resistance cassette was removed via flp-mediated recombination. The R132H mutation corresponds to the vanishing white matter causing human R136H allele. |
