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Allele : Lnpep<tm1.1Mrl> leucyl/cystinyl aminopeptidase; targeted mutation 1.1, Merck Research Laboratory

Primary Identifier  MGI:6434026 Allele Type  Targeted
Attribute String  Not Specified Gene  Lnpep
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  The H464Y and H468Y point mutations was introduced into exon 6 (TKIIAHELAHQWFGN to TKIIAYELAYQWFGN). A positive selection marker (puromycin resistance) was flanked by F3 sites and introduced into intron 6. The constitutive point mutation allele was generated after Flp-mediated recombination.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele