Primary Identifier | MGI:6434494 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(RBP3-ELOVL4*)M69-123Mrl |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A plasmid containing the human RBP3 promoter, a rabbit beta-globin intron and the human mutant ELOVL4 cDNA harboring the AACTT deletion resulting in progressive photoreceptor degeneration was engineered. Line M69-123 has 1 transgenic copy integrated and shows lowest expression level in ONL. |