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Allele : Runx1<tm4.1Itan> runt related transcription factor 1; targeted mutation 4.1, Ichiro Taniuchi
Primary Identifier  MGI:6441730 Allele Type  Targeted
Attribute String  Not Specified Gene  Runx1
Transmission  Germline Strain of Origin  (129 x C57BL/6)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The translation start codon, AUG, in exon 2 was replaced with a stop codon, UAG, and removed around 200 bp upstream of the putative transcriptional start site of promoter 2. This allele maintains expression from promoter 1 (P1), but not promoter 2 (P2). Cre-mediated recombination removed the flocked neomycin resistance cassette.
  • mutations:
  • Insertion,
  • Nucleotide substitutions,
  • Intragenic deletion
  • synonyms:
  • Runx1<P2TAG>,
  • Runx1<P2TAG>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

3 Publication categories

Trail: Allele




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