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Allele : Runx1<tm6.1Itan> runt related transcription factor 1; targeted mutation 6.1, Ichiro Taniuchi
Primary Identifier  MGI:6441734 Allele Type  Targeted
Attribute String  Not Specified Gene  Runx1
Transmission  Germline Strain of Origin  (129 x C57BL/6)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin resistance cassette replaced exons 1a and 1b. Cre-mediated recombination removed the selection cassette. The translation start codon, AUG, in exon 2 was replaced UAA to created an aberrant splice acceptor site. Another round of cre-mediated recombination removed the neomycin resistance cassette inserted into intron 2.
  • mutations:
  • Intragenic deletion,
  • Insertion,
  • Single point mutation
  • synonyms:
  • Runx1<deltaP1:P2TAA>,
  • Runx1<deltaP1:P2TAA>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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